Longer, fuller eyelashes, obtained in just a few weeks thanks to a serum: the promise that is driving TikTok and the beauty aisles crazy. Many apply it every evening, as a simple treatment. Until the day when the look itself seems to change.
On December 11, 2025, the National Health Security Agency (ANSES) issued a clear alert. It targets certain serums to make eyelashes grow, which are likely to cause irreversible effects: change in eye color and melting of fat around the eye socket, resulting in clearly deepened dark circles.
Why is ANSES targeting these eyelash serums?
In this text, the agency indicates that these products contain , or , we can read in a press release cited by Here. In other words, the risk goes far beyond eyelash growth alone.
ANSES describes a case: in February 2025, a woman who had applied a serum for five months saw one of her irises darken. , she specifies. The agency recalls that; in this context, while the users of these serums.
How these serums act on the eyes
Prostaglandins change the pigmentation of the iris and tissues around the eye when used as eye drops to treat glaucoma. In this medical context, the expected benefit on the disease justifies these side effects.
Applied every evening to the base of the eyelashes, these molecules can also cause periorbital fat to melt, making dark circles appear deeper and the look look tired. The spectacular lengthening of the eyelashes is then accompanied by a darker eye, framed by marked shadows under the lower eyelid.
How to check your serum and protect your eyes
On the INCI list, look for names ending in -prost or mentions like isopropyl cloprostenate. These are strong signals of the presence of prostaglandin analogs in an eyelash serum.
- Seek the advice of an ophthalmologist before regular use.
- Stop the serum and report any side effects online.
These products remain authorized, but their safety is assessed at European level. ANSES advises limiting long courses of treatment, seeking medical advice in case of doubt and declaring any suspicious effects on the cosmetovigilance portal.
Which eyelash serums are affected?
These are serums containing prostaglandin analogues, often identified by names with -prost or the mention isopropyl cloprostenate.
Is eye color change reversible?
ANSES describes a darkening of the iris and a melting of the fat around the eye as irreversible effects, which generally do not disappear.
What should I do if I have already used these serums?
Stop the product, monitor any change in the appearance of the iris or dark circles, consult a doctor and report the adverse effect on the cosmetovigilance portal.
